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FK-453
Item number: Cay45327-1
FK-453 is an adenosine A1 receptor antagonist (Ki = 18 nM). It is selective for the adenosine A1 receptor over the adenosine A2A and A3 receptors (Kis = 1,300 and 2,800 nM, respectively). FK-453 reduces adenosine-induced negative inotropic activity in isolated guinea pig atrial strips (IC50 = 560 pM).2 It has...
| Keywords: | (2E)-1-[(2R)-2-(2-hydroxyethyl)-1-piperidinyl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2-propen-1-one |
| Application: | Adenosine A1 receptor antagonist |
| CAS | 121524-18-3 |
| MW: | 375.47 D |
From 174.00€
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FK-453
Item number: TGM-T27323-100mg
Description: FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity. Target: Adenosine Receptor. Smiles: C(=C/C(=O)N1[C@@H](CCO)CCCC1)\C=2C(=NN3C2C=CC=C3)C4=CC=CC=C4
| Keywords: | FK453 , FK 453 |
| CAS | 121524-18-3 |
| MW: | 375.46 D |
From 200.00€
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