2 products were found matching "1214265-58-3"!

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Item number: Cay19177-1

NUAK1 (also known as AMPK-related kinase 5) and NUAK2 (also known as SNF1/AMPK-related kinase) are members of the AMP-activated protein kinase (AMPK) family of protein kinases that are activated by the liver kinase B1 tumor suppressor kinase. NUAK kinases are thought to have roles in regulating cell adhesion, cancer...

Keywords:	N-[3-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-propanamide
Application:	Selective NUAK1 / NUAK2 inhibitor
CAS	1214265-58-3
MW:	497 D

From 49.00€ *

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WZ4003

Item number: TGM-T6291-100mg

Description: WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively. It is no significant inhibition on 139 other kinases. Target: AMPK. Smiles: CCC(=O)Nc1cccc(Oc2nc(Nc3ccc(cc3OC)N3CCN(C)CC3)ncc2Cl)c1. References: Banerjee S, et al. Biochem J. 2014,...

Application:	Selective NUAK1 / NUAK2 inhibitor
CAS	1214265-58-3
MW:	496.99 D

From 41.00€ *

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