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EG 00229 (trifluoroacetate salt)
Item number: Cay33937-1
EG 00229 is an antagonist of neuropilin-1 (NRP-1). It inhibits the binding of VEGF-A to porcine aortic endothelial cells expressing NRP-1, but not VEGFR2, with an IC50 value of 8 µM. EG 00229 (100 µM) reduces VEGF-A-induced migration of human umbilical vein endothelial cells (HUVECs) and enhances the cytotoxicity of...
| Keywords: | N2-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine, 2,2,2-trifluoroacetate |
| Application: | NRP-1 antagonist |
| CAS | 1210945-69-9 |
| MW: | 611.6 D |
From 65.00€
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EG00229
Item number: TGM-T11153-100mg
Description: EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain with an IC50 value of 3 µM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2. Target: Others. Smiles:...
| CAS | 1210945-69-9 |
| MW: | 611.6 D |
From 43.00€
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