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JZL 195
JZL 195

Item number: Cay13668-5

Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively). It poorly inhibits neuropathy...
Keywords: 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
Application: FAAH / MAGL inhibitor
CAS 1210004-12-8
MW: 433.5 D
From 95.00€ *
Review
JZL195
JZL195

Item number: TGM-T2338-100mg

Description: JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor. Target: FAAH, Autophagy, Lipase. Smiles: [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2)cc1. References: Long JZ, et al. Proc Natl Acad Sci U S A. 2009 Dec 1,106(48):20270-5.
CAS 1210004-12-8
MW: 433.46 D
From 38.00€ *
Review