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WT-161
Item number: TGM-T7385-100mg
Description: WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM). Target: Apoptosis, HDAC. Smiles: N(C1=CC=C(C=NNC(CCCCCCC(NO)=O)=O)C=C1)(C2=CC=CC=C2)C3=CC=CC=C3. References: Hideshima T , Qi J , Paranal R M , et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome...
| Application: | HDAC6 inhibitor |
| CAS | 1206731-57-8 |
| MW: | 458.55 D |
From 37.00€
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WT161
Item number: Cay21099-1
WT161 is a potent inhibitor of HDAC6 with an IC50 value of 0.40 nM. It is selective for HDAC6 over HDAC3 (IC50 = 51.61 nM) and induces alpha-tubulin acetylation, an HDAC6-dependent process, with minimal effect on global lysine acetylation. WT161 inhibits growth of patient-derived multiple myeloma cell lines with...
| Keywords: | 8-(hydroxyamino)-8-oxo-octanoic acid, 2-[[4-(diphenylamino)phenyl]methylene]hydrazide |
| Application: | HDAC6 inhibitor |
| CAS | 1206731-57-8 |
| MW: | 458.6 D |
From 44.00€
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