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Filgotinib
Filgotinib

Item number: Cay17669-5

Filgotinib is a JAK1 inhibitor (IC50 = 10 nM). It is selective for JAK1 over JAK3 (IC50 = 810 nM) but also inhibits JAK2 and tyrosine kinase 2 (Tyk2, IC50s = 28 and 116 nM, respectively), as well as Abl, FLT1, -3, and -4, FMS, Mer, and TBK1 activity by greater than 35% in a panel of 177 tyrosine kinases at 1 µM....
Keywords: GLPG0634,...
Application: JAK1 inhibitor
CAS 1206161-97-8
MW: 425.5 D
From 76.00€ *
Review
GLPG0634
GLPG0634

Item number: SYN-1158-M001

Soluble in DMSO. GLPG0634 is a novel and specific inhibitor of JAK1 and JAK2 with IC(50) of 10nM and 28nM respectively measured by in vitro kinase assays (ATP 2µM). In particular GLPG0634, while being a potent inhibitor of JAK1 and JAK2 does not inhibit TYK2 or JAK3, and GLPG0634 exhibits a dramatically improved in...
Keywords: GLPG-0634, Filgotinib
Application: JAK1 / JAK2 inhibitor
CAS 1206161-97-8
MW: 425,5 D
From 250.00€ *
Review
GLPG-0634
GLPG-0634

Item number: LKT-G4662.1

JAK1 inhibitor.
Keywords: GLPG0634, Filgotinib
Application: JAK1 inhibitor
CAS 1206161-97-8
MW: 425.5 D
From 149.00€ *
Review