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AS-1949490
Item number: Cay17627-5
SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) negatively regulates the insulin signaling pathway by hydrolyzing phosphatidylinositol-3,4,5-trisphosphate. Its activity has been implicated in the pathogenesis of insulin resistance and type 2 diabetes. AS-1949490 is a small molecule inhibitor of SHIP2 (IC50s...
| Keywords: | 3-[(4-chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]-2-thiophenecarboxamide |
| Application: | SHIP2 inhibitor |
| CAS | 1203680-76-5 |
| MW: | 371.9 D |
From 51.00€
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AS1949490
Item number: TGM-T14327-100mg
Description: AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5' phosphatase 2) inhibitor, with an IC50 of 620 nM. Target: Phosphatase. Smiles: C[C@H](NC(=O)c1sccc1OCc1ccc(Cl)cc1)c1ccccc1....
| Application: | SHIP2 inhibitor |
| CAS | 1203680-76-5 |
| MW: | 371.88 D |
From 33.00€
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