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Tenidap
Tenidap

Item number: Cay17413-10

Tenidap is a COX-1 selective non-steroidal anti-inflammatory drug (IC50s = 30 µM for COX-1, COX-2, and 5-lipoxygenase (5-LO), respectively). It has anti-inflammatory and antirheumatic properties. In vitro, it inhibits prostaglandin D2 (PGD2), leukotriene B4 (LTB4), and prostaglandin E2 (PGE2) synthesis (IC50s =...
Keywords: CP 66,248, (3Z)-5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide
Application: Antiinflammatory
CAS 120210-48-2
MW: 320.8 D
From 53.00€ *
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Tenidap
Tenidap

Item number: TGM-T17036-100mg

Description: Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities. Target: DNA/RNA Synthesis, COX. Smiles: NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12. References: Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual...
Keywords: CP-66248
Application: Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1)
CAS 120210-48-2
MW: 320.75 D
From 30.00€ *
Review