4 products were found matching "1201438-56-3"!
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IPI-145
Item number: Cay16800-1
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kgamma and PI3Kdelta (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kgamma and PI3Kdelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and...
| Keywords: | Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone |
| Application: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416.9 D |
From 92.00€
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IPI-145
Item number: SYN-1175-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. IPI-145 is a potent, oral inhibitor of Class I phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma (IC(50) of 243 pM and 50nM), and is clinically active in patients with advanced hematological malignancies. Target: PI3K , Kinase Group: Atypical (PIKK) ,...
| Keywords: | IPI 145 |
| Application: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416,9 D |
From 139.00€
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IPI-145
Item number: LKT-I6132.1
IPI-145 is an inhibitor of p110 PI3K that exhibits anticancer chemotherapeutic, immunosuppressive, and anti-inflammatory activities. In clinical trials, IPI-145 displays potential benefit in the treatment of chronic lymphocytic leukemia (CLL). IPI-145 inhibits proliferation of B and T cells, inhibits neutrophil...
| Keywords: | INK1197 |
| Application: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416.86 D |
From 205.00€
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Duvelisib, Free Base (INK-1197, IPI-145, CAS...
Item number: LC-D-8147_100mg
Soluble in DMSO
| Keywords: | Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone |
| Application: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416,8 D |
From 94.00€
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