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CBL0137
Item number: Cay19110-1
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-kappaB with an EC50 of 0.47 µM. It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-kappaB and promoting cancer cell death. CBL0137 has broad...
| Keywords: | CBLC137, Curaxin 137, 1,1'-[9-[2-[(1-methylethyl)amino]ethyl]-9H-carbazole-3,6-diyl]bis-ethanone |
| Application: | Curaxin, p53 activator, NF-kappaB inhibitor |
| CAS | 1197996-80-7 |
| MW: | 336.4 D |
From 71.00€
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CBL0137
Item number: TGM-T4126-100mg
Description: CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 µM) and inhibits NF-kappaB (EC50: 0.47 µM). It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-kappaB and promoting cancer cell death. CBL0137 has broad...
| Keywords: | Curaxin 137, CBLC137 |
| Application: | Curaxin, p53 activator, NF-kappaB inhibitor |
| CAS | 1197996-80-7 |
| MW: | 336.43 D |
From 42.00€
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