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ALK-IN-1
ALK-IN-1

Item number: Cay18775-10

ALK-IN-1 is an analog of AP26113, a phosphine oxide-containing ALK inhibitor. ALK-IN-1 potently inhibits ALK (IC50 = 0.07 nM) over IGF-1R and InsR (IC50s = 3.2 and 100 nM, respectively). It drives cell death in (ALK+) Karpas-299 lymphoma cells with an IC50 value of 41.5 nM, while killing (ALK-) U937 cells with an...
Keywords: 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
Application: ALK inhibitor
CAS 1197958-12-5
MW: 529 D
From 74.00€ *
Review
AP-26113
AP-26113

Item number: LKT-A600002.100

Keywords: Brigatinib Analog, AP26113
Application: ALK inhibitor
CAS 1197958-12-5
MW: 529.02 D
From 176.00€ *
Review