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Item number: Cay9001962-1

Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product PGH2 (Cay-17020) into the biologically active PGE2 (Cay-14010). Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. AF3485 is a selective 3-aminocarbazole inhibitor...

Keywords:	CAY10686, N-[9-(2-hydroxyethyl)-9H-carbazol-3-yl]-2-(trifluoromethyl)-benzamide
Application:	mPGES-1 inhibitor
CAS	1195786-61-8
MW:	398.4 D

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