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Item number: Cay62575-5

N,N-Dimethylsphingosine is a metabolite of sphingosine and an inhibitor of sphingosine kinase (SPHK) with Ki values of 3.1, 6.8, and 2.3 µM in U937, PC12, and Swiss 3T3 cell extracts, respectively. It is selective for SPHK over PKC in PC12 cells when used at a concentration of 10 µM.Formal Name:...

Keywords:	2S-(dimethylamino)-4E-octadecene-1,3R-diol
Application:	Sphingosine kinase inhibitor
CAS	119567-63-4
MW:	327.6 D

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N,N-dimethyl-Sphingosine

Item number: LKT-S6131.5

N,N-Dimethyl sphingosine inhibits sphingosine kinase 1 (Sphk1) and PKC and exhibits neuromodulatory and anticancer chemotherapeutic activities. This compound activates protein phosphatase 2A (PP2A) activity by suppressing ANP32A inhibition of PP2A in vitro. Additionally, this compound inhibits cell proliferation and...

Keywords:	N,N-Dimethyl-D-erythro-sphingosine
Application:	Sphingosine kinase inhibitor
CAS	119567-63-4
MW:	327.5 D

169.00€ *

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