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PHT-427
Item number: LKT-P3076.5
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
| Keywords: | PHT427 |
| Application: | PDK1 / Akt inhibitor |
| CAS | 1191951-57-1 |
| MW: | 409.61 D |
From 104.00€
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PHT-427
Item number: Cay24188-5
PHT-427 is an inhibitor of the serine/threonine kinases Akt and phosphoinositide-dependent protein kinase-1 (PDPK1) with Ki values of 2.7 and 5.2 µM, respectively, that selectively binds to the pleckstrin homology binding domain of both kinases. PHT-427 (10 µM) inhibits PDPK1 and Akt autophosphorylation in BxPC-3...
| Keywords: | Akt Inhibitor XIV, 4-dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide |
| Application: | PDK1 / Akt inhibitor |
| CAS | 1191951-57-1 |
| MW: | 409.6 D |
From 59.00€
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PHT-427
Item number: TGM-T2420-100mg
Description: PHT-427 (CS-0223) is a dual Akt (Ki: 2.7 µM) and PDPK1 (Ki: 5.2 µM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1). Target: Akt, Apoptosis, PDK. Smiles: CCCCCCCCCC CCc1ccc(cc1)S(=O)(=O)Nc1nncs1. References: Meuillet EJ, et al. Mol Cancer Ther, 2010, 9(3), 706-717.
| Keywords: | PHT 427, CS-0223 |
| CAS | 1191951-57-1 |
| MW: | 409.61 D |
From 38.00€
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