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Item number: TGM-T8515-100mg

Description: Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory. Target: PDE. Smiles: O=c1nc(Cc2ccccn2)[nH]c2n(ncc12)C1CCOCC1. References: Cornelia Dorner-Ciossek, R. Giovannini, Holger Rosenbrock. BI 409306, A NOVEL PHOSPHODIE STERASE 9A INHIBITOR,...

Keywords:	BI-409306
Application:	Potent, selective PDE9A inhibitor
CAS	1189767-28-9
MW:	311.34 D

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BI-409306

Item number: Cay30375-1

BI-409306 is a potent and selective phosphodiesterase 9A (PDE9A) inhibitor with IC50 values of 65 and 168 nM for the human and rat enzymes, respectively. It is selective for PDE9A over PDE2A, -3A, -4B, -5A, -6AB, -7A and -10A and 95 non-PDE targets at 10 µM but does inhibit human PDE1A and PDE1C (IC50s = 1.45 and...

Keywords:	1,5-dihydro-6-(2-pyridinylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
Application:	Potent, selective PDE9A inhibitor
CAS	1189767-28-9
MW:	311.3 D

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