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Item number: Cay19171-5

PF-4800567 is a selective inhibitor of casein kinase 1epsilon (CK1epsilon, IC50 = 32 nM) with greater than 20-fold selectivity over CK1delta. It blocks CK1epsilon-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins important for maintaining circadian rhythms in cells. PF-4800567 has...

Keywords:	3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Application:	CSNK1E inhibitor
CAS	1188296-52-7
MW:	359.8 D

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PF-4800567

Item number: TGM-T5056-100mg

Description: PF-4800567 is a selective inhibitor of casein kinase 1epsilon (CK1epsilon, IC50 = 32 nM) with greater than 20-fold selectivity over CK1delta. Target: Casein Kinase. Smiles: Nc1ncnc2n(nc(COc3cccc(Cl)c3)c12)C1CCOCC1. References: Walton KM, et al. Selective inhibition of casein kinase 1 epsilon minimally...

Application:	CSNK1E inhibitor
CAS	1188296-52-7
MW:	359.81 D

From 37.00€ *

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