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Item number: TGM-T4635-100mg

Description: Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. Target: Prostaglandin Receptor, Others. Smiles:...

Keywords:	APD811
Application:	Targets prostacyclin receptor (PTGIR)
CAS	1187856-49-0
MW:	431.91 D

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Ralinepag

Item number: Cay30009-1

Ralinepag is a prostaglandin I2 (PGI2) receptor (IP) agonist (Ki = 3 nM). It is selective for IP over the PGD2 receptor (DP1) and the PGE2 receptor subtypes EP1-4 (Kis = 2,600, 9,600, 611, 143, and 678 nM, respectively, in radioligand binding assays). Ralinepag induces cAMP accumulation in CHO-K1 cells expressing...

Keywords:	2-[[trans-4-[[[[(4-chlorophenyl)phenylamino]carbonyl]oxy]methyl]cyclohexyl]methoxy]-acetic acid
Application:	Prostanoid IP receptor agonist
CAS	1187856-49-0
MW:	431.9 D

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