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ALW-II-41-27
ALW-II-41-27

Item number: TGM-T4344-100mg

Description: ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy. Target: Ephrin Receptor. Smiles: CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cncc(c4)-c4cccs4)c3)cc2C(F)(F)F)CC1. References: Choi, et al. Discovery and structural analysis of Eph...
Keywords: Eph receptor tyrosine kinase inhibitor
CAS 1186206-79-0
MW: 607.69 D
From 62.00€ *
Review
ALW-II-41-27
ALW-II-41-27

Item number: Cay25275-1

ALW-II-41-27 is a multi-kinase inhibitor that inhibits EphB2, EphA3, Kit, FMS, VEGFR2/KDR, FLT1, FGR, Src, Lyn, BMX, and Bcr-Abl in tyrosine kinase-transformed Ba/F3 cells (EC50s = 50s = 51 and 14 nM, respectively) as well as wild-type and mutant RET kinases (IC50s = 24.7, 94.2, and 15.8 nM for wild-type, RETV804L,...
Keywords: N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[[[5-(2-thienyl)-3-pyridinyl]carbonyl]amino]-be...
Application: Multi-kinase inhibitor
CAS 1186206-79-0
MW: 607.7 D
From 85.00€ *
Review