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IKK 16 hydrochloride
Item number: TGM-T15557-100mg
Description: IKK 16 hydrochloride is a selective inhibitor of IKK2 (IC50: 40 nM), the IKK complex (IC50: 70 nM), and IKK1 IkappaB kinase (IKK) (IC50: 200 nM), as well as leucine-rich repeat kinase-2 (LRRK2, IC50: 50 nM). Target: Others. Smiles: Cl.O=C(NN1CCC(CC1)N1CCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1....
| Application: | IkappaB kinase inhibitor |
| CAS | 1186195-62-9 |
| MW: | 520.09 D |
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IKK-16 (hydrochloride)
Item number: Cay13313-5
IKK-16 is a potent inhibitor of IkappaB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKalpha, IKKbeta, and IKK complex, respectively, in cell-free assays. It is effective in cells and in animals and has been used delineate the role of NF-kappaB signaling in diverse contexts. IKK-16 has also been...
| Keywords: | IKK Inhibitor VII, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone,... |
| Application: | IkappaB kinase inhibitor |
| CAS | 1186195-62-9 |
| MW: | 520.1 D |
From 128.00€
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