2 products were found matching "1186195-60-7"!

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Item number: Cay14961-10

Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depression. Eight subtypes (1-8) and multiple splice variants of the...

Keywords:	3-[2-(2-methyl-4-thiazolyl)ethynyl]-pyridine, monohydrochloride
Application:	mGlu5a receptor antagonist
CAS	1186195-60-7
MW:	236.7 D

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MTEP hydrochloride

Item number: TGM-T7515-100mg

Description: MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively). Target: GluR. Smiles: Cl.Cc1nc(cs1)C#Cc1cccnc1. References: NMDA but not AMPA glutamatergic receptors are involved in the antidepressant-like activity of MTEP during the forced swim test in...

Keywords:	3-((2-Methyl-1,3-thiazol-4-yl)ethyn-yl)pyridine hydrochloride, MTEP
Application:	mGlu5a receptor antagonist
CAS	1186195-60-7
MW:	236.72 D

From 34.00€ *

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