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Item number: Cay34495-1

NVP-BVU972 is an inhibitor of Met kinase (IC50 = 14 nM). It is selective for Met over a panel of 62 additional kinases (IC50s = >1 µM for all). It inhibits proliferation of Met-amplified GTL-16 gastric, MKN45 gastric, and EBC-1 lung cancer cells (IC50s = 66, 32, and 82 nM, respectively). NVP-BVU972 inhibits Met...

Keywords:	6-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]-quinoline
Application:	Met kinase inhibitor
CAS	1185763-69-2
MW:	340.4 D

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