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SAR-020106
SAR-020106

Item number: SYN-1189-M001

Soluble in DMSO. SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC(50) of 13.3nM on the isolated human enzyme. This compound abrogates an etoposide-induced G(2) arrest with an IC(50) of 55nM in HT29 cells, and significantly enhances the cell killing of gemcitabine and SN38 by 3.0- to...
Keywords: SAR020106
Application: Chk1 inhibitor
CAS 1184843-57-9
MW: 382,9 D
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