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Item number: Cay21753-10

MK-886 is a potent, selective inhibitor of 5-lipoxygenase-activating protein (FLAP) that prevents 5-lipoxygenase activation in vivo and inhibits leukotriene biosynthesis in leukocytes with an IC50 of 2.5 nM. In human whole blood, leukotriene biosynthesis is inhibited by MK-886 with an IC50 of 1.1 µM.Formal Name:...

Keywords:	L-663,536,...
Application:	FLAP inhibitor
CAS	118414-82-7
MW:	472.1 D

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