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Item number: Cay45243-1

An inhibitor of Chk1 and WEE1 (IC50s = 47 and 97 nM, respectively), selective for Chk1 and WEE1 over PKC (IC50 = 3.4 µM) and Cdk4 (IC50 = 3.75 µM), selective for Chk1 and WEE1 over c-Src and the PDGF and FGF receptors (IC50s = >50 µM for all), and other CDKs (IC50s = >50 µM), sensitizes SKOV3 and OVCAR-3 ovarian...

Keywords:	9-hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, monohydrate
Application:	Chk1 / WEE1 inhibitor
CAS	1177150-89-8
MW:	346.34 D

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