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Item number: SYN-1163-M001

Soluble in DMSO. PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent...

Keywords:	PF4618433
Application:	PYK2 inhibitor
CAS	1166393-85-6
MW:	445,5 D

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PF-4618433

Item number: TGM-T22397-2mg

Description: PF-4618433 is a dual inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Target: Others. Smiles: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cc(COc2cccnc2)n[nH]1)C(C)(C)C

Application:	PYK2 inhibitor
CAS	1166393-85-6
MW:	445.52 D

141.00€ *

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