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Item number: Cay16888-10

Pyr3 is a pyrazole compound that selectively antagonizes the transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 µM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05...

Keywords:	1-[4-[(2,3,3-trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid, ethyl ester
Application:	TRPC3 antagonist
CAS	1160514-60-2
MW:	456.6 D

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