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ER819762
ER819762

Item number: TGM-T27279-5mg

Description: ER819762, an antagonist of the prostaglandin E2 EP4 receptor, inhibits Th1 differentiation and Th17 expansion. Target: Others. Smiles: C(C)N1C2(C=3N(C1=O)CC=4C([C@@H](C)C3)=C(OC)C=C(OC)C4)CCN(CC5=CC(C)=CC(C)=C5)CC2. References: Jones VC, Birrell MA, Maher SA, Griffiths M, Grace M, O'Donnell VB, Clark...
Keywords: ER 819762, ER-819762
Application: EP4 antagonist
CAS 1155773-15-1
MW: 489.65 D
861.00€ *
Review
ER-819762
ER-819762

Item number: Cay10531-1

ER-819762 is an antagonist of the prostaglandin E2 (PGE2, Cay-14010) receptor subtype EP4 (IC50 = 70 nM). It is selective for EP4 over EP1, EP2, and EP3 in a cAMP reporter assay at 10 µM. ER-819762 reduces differentiation of mouse helper T cells when used at concentrations ranging from 0.1 to 10 nM and decreases...
Keywords: (10S)-1'-[(3,5-dimethylphenyl)methyl]-2-ethyl-5,10-dihydro-7,9-dimethoxy-10-methyl-spiro[1H-imidazo[1,5-b][2]benzazepine-1...
Application: EP4 antagonist
CAS 1155773-15-1
MW: 489.7 D
From 106.00€ *
Review