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Item number: Cay15045-10

Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 µM, dofetilide has pro-arrhythmic activity,...

Keywords:	Tikosyn, UK 68789, N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide
Application:	Voltage-gated potassium channel (KCNH2) blocker
CAS	115256-11-6
MW:	441.6 D

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