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Item number: TGM-T3148-5mg

Description: MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the cellular efflux of drugs, xenobiotics, and their conjugates. MK-571 sodium can...

Keywords:	Verlukast sodium, L-660711, MK-571 sodium salt, MK571, Propanoic acid, L-660711 sodium salt, L-660711 (sodium salt)
CAS	115103-85-0
MW:	537.07 D

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MK-571 (sodium salt)

Item number: Cay70720-5

MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...

Keywords:	L-660,711, (E)-3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic...
Application:	CysLT1 receptor antagonist
CAS	115103-85-0
MW:	537.1 D

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