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Item number: AG-CR1-3520-M001

Soluble in DMSO (at least 10 mg/ml). Specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.

Keywords:	(3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
Application:	Aurora A kinase inhibitor
CAS	1148118-92-6
MW:	253,3 D

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