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WYE-125132
Item number: Cay18372-1
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin (Cay-13346)) and regulate different pathways. WYE-125132 is an ATP-competitive inhibitor of mTOR...
| Keywords: | WYE-132,... |
| Application: | mTOR inhibitor |
| CAS | 1144068-46-1 |
| MW: | 519.6 D |
From 58.00€
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WYE-132
Item number: TGM-T6346-100mg
Description: WYE-125132 (WYE-132 (WYE-125132)) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM, highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR. Target: mTOR, Apoptosis. Smiles: CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCC4(CC3)OCCO4)c2n1. References: Yu K,...
| Keywords: | WYE-125132, WYE125132, WYE 125132 |
| Application: | mTOR inhibitor |
| CAS | 1144068-46-1 |
| MW: | 519.6 D |
From 38.00€
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