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Item number: Cay19353-10

VU0255035 is a competitive, orthosteric antagonist of the muscarinic M1 receptor (IC50 = 130 nM). It displays at least 75-fold selectivity for M1 over other muscarinic receptors, as well as a panel of receptors, ion channels, and transporters. VU0255035 is effective in cells and in vivo and brain penetrating,...

Keywords:	ML-012, N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Application:	Muscarinic M1 receptor antagonist
CAS	1135243-19-4
MW:	432.5 D

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VU 0255035

Item number: TGM-T23508-100mg

Description: VU 0255035 is a highly selective, competitive, and brain-penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM, used to reduce pilocarpine-induced seizures in mice and to examine the role of the M1 receptor in diverse situations. Target: AChR. Smiles:...

CAS	1135243-19-4
MW:	432.52 D

From 31.00€ *

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