Dasatinib-d8 is intended for use as an internal standard for the quantification of dasatinib (Cay-11498) by GC- or LC-MS. Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. It is effective at sub-nanomolar concentrations, inhibiting Src, Abl,...

Description: Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor. Smiles: N(C1=CC(N2C(C(N(CCO)C(C2([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])=NC(C)=N1)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3