Description: Paclitaxel-d5 is a deuterated compound of Paclitaxel. Paclitaxel has a CAS number of 33069-62-4. Paclitaxel is a cyclodecane isolated from the bark of the Pacific yew tree. It stabilizes microtubules in their polymerized form leading to cell death. Target: ADC Cytotoxin. Smiles:...

Paclitaxel-d5 contains five deuterium atoms. It is intended for use as an internal standard for the quantification of paclitaxel (Cay-10461) using GC- or LC-MS. Paclitaxel is cytotoxic against a variety of cancer cell lines with IC50 values ranging from 2.5-7.5 nM. It disrupts multipolar spindle formation, inducing...