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IWR-1-exo
IWR-1-exo

Item number: Cay13598-10

Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to beta-catenin activation of gene transcription. IWR-1-exo is a diastereomer of...
Keywords: 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-benzamide
Application: IWR-1-endo control
CAS 1127442-87-8
MW: 409.4 D
From 104.00€ *
Review
exo-IWR-1
exo-IWR-1

Item number: TGM-T22775-100mg

Description: exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/beta-catenin signaling pathway. Target: Wnt/beta-catenin. Smiles: [H][C@@]12C[C@]([H])(C=C1)[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])c1ccc(cc1)C(=O)Nc1cccc2cccnc12
Keywords: exo-IWR 1
CAS 1127442-87-8
MW: 409.44 D
From 29.00€ *
Review