3 products were found matching "112522-64-2"!
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CI-994
Item number: Cay12084-5
CI-994 is an inhibitor of histone deacetylase 1 (HDAC1), HDAC2, and HDAC3 (IC50s = 0.9, 0.9, and 1.2 µM, respectively). It is selective for these HDACs over HDAC8 (IC50 = >20 µM). CI-994 inhibits the growth of HCT116 colon cancer cells but not human mammary epithelial cells (HMECs, IC50s = 4 and >50 µM,...
| Keywords: | Goe 5549, N-Acetyldinaline, PD 123654, Tacedinaline, 4-(acetylamino)-N-(2-aminophenyl)-benzamide |
| Application: | HDAC inhibitor |
| CAS | 112522-64-2 |
| MW: | 269.3 D |
From 36.00€
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CI-994, Free Base...
Item number: C5071-65.50
CI-994 is a histone deacetylase (HDAC) inhibitor and induces histone hyperacetylation in living cells. CI-994 inhibited HDAC-1 and HDAC-2 but not the prototypical histone acetyltransferase GCN5. Melting Point: 235-242ºC, Solubility: Soluble in DMSO at 66mg/ml, very poorly soluble in ethanol and water, maximum...
| CAS | 112522-64-2 |
| MW: | 269.30 |
263.00€
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Tacedinaline
Item number: TGM-T1888-100mg
Description: Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity. Target: Apoptosis, HDAC. Smiles: N(C(=O)C1=CC=C(NC(C)=O)C=C1)C2=C(N)C=CC=C2. References: Moradei OM, et al. J Med Chem. 2007, 50(23), 5543-5546.
| Keywords: | N-acetyldinaline, Acetyldinaline, PD-123654, Goe-5549, CI994 |
| Application: | Targets histone deacetylase 1/2 [EC:3.5.1.98] (HDAC1_2) |
| CAS | 112522-64-2 |
| MW: | 269.3 D |
From 41.00€
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