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Item number: Cay19991-10

AZ 3146 is an inhibitor of the monopolar spindle 1 (Mps1) checkpoint kinase (IC50 = 35 nM). It displays selectivity over 46 other kinases including Cdk1 and Aurora kinase B. It has been shown to inhibit the recruitment of Mad1, Mad2, and centromere protein E (CENP-E) to kinetochores. AZ 3146 can be used with...

Keywords:	Mps1 Inhibitor III,...
Application:	TTK / Mps1 inhibitor
CAS	1124329-14-1
MW:	452.6 D

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AZ3146

Item number: TGM-T2689-100mg

Description: AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM. Target: Kinesin. Smiles: O=C1N(C=2C(N1C)=CN=C(NC3=C(OC)C=C(OC4CCN(C)CC4)C=C3)N2)C5CCCC5. References: Hewitt L, et al. J Cell Biol, 2010, 190(1), 25-34.

Keywords:	AZ 3146
CAS	1124329-14-1
MW:	452.55 D

From 34.00€ *

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