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Sitravatinib
Sitravatinib

Item number: Cay27338-5

Sitravatinib is a multi-kinase inhibitor. It inhibits 35 kinases (IC50s = 0.5-5,550 nM) in a panel of 55 receptor tyrosine kinases (RTKs). Sitravatinib reduces proliferation of A-673, LPS141, MPNST, DDLS, and Saos-2 cancer cells (IC50s = 1,750, 340.1, 705.7, 266, and 1,830 nM, respectively) and decreases...
Keywords: MGCD-516,...
Application: Multi-kinase inhibitor, receptor tyrosine kinase inhibitor
CAS 1123837-84-2
MW: 629.7 D
From 85.00€ *
Review
Sitravatinib
Sitravatinib

Item number: TGM-T4349-100mg

Description: Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRalpha/beta, PDGFR, and Axl. Target: VEGFR, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor, FLT, Discoidin Domain Receptor (DDR). Smiles:...
Keywords: MG516, MGCD516
Application: Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO)
CAS 1123837-84-2
MW: 629.68 D
From 45.00€ *
Review