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Item number: TGM-T4138-100mg

Description: UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 µM. Target: transporter. Smiles: COc1ccc(cc1)C1C(C#N)=C(N)OC2=C1C(=O)CC(C2)c1cccc2ccccc12. References: Abrahamsen B, et al. Allosteric modulation of an excitatory amino acid transporter: the...

Keywords:	UCPH 101
Application:	GLAST-1 inhibitor
CAS	1118460-77-7
MW:	422.48 D

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UCPH-101

Item number: Cay21460-1

UCPH-101 is a noncompetitive inhibitor of excitatory amino acid transporter 1 (EAAT1), which takes up extracellular glutamate in the central nervous system. UCPH-1 is selective for EAAT1 over EAAT2 and EAAT3 with IC50 values of 0.66, >300, and >300 µM, respectively, in a radioligand uptake assay using HEK293 cells...

Keywords:	2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(1-naphthalenyl)-5-oxo-4H-1-benzopyran-3-carbonitrile
Application:	GLAST-1 inhibitor
CAS	1118460-77-7
MW:	422.5 D

From 85.00€ *

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