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MD2-IN-1
MD2-IN-1

Item number: TGM-T4231-100mg

Description: MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 µM for the recombinant human MD2 (rhMD2). Target: TLR. Smiles: COc1ccc(cc1OC)C(=O)\C=C\c1cc(OC)c(OC)c(OC)c1. References: Zhang Y, et al. Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory...
Application: Chalcone derivative, MD-2 (Lymphocyte antigen 96)-LPS interaction inhibitor
CAS 111797-22-9
MW: 358.39 D
From 55.00€ *
Review
MD2-IN-1
MD2-IN-1

Item number: Cay38323-1

MD2-IN-1 is a chalcone derivative and an inhibitor of the interaction between myeloid differentiation 2 (MD-2) and LPS. It inhibits the interaction between MD-2 and LPS in a cell-free assay when used at a concentration of 0.1 µM. It inhibits LPS-induced increases in the levels of Tnf-alpha and Il-6 secreted from...
Keywords: Myeloid Differentiation 2 Inhibitor 1, 1-(3,4-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one
Application: Chalcone derivative, MD-2 (Lymphocyte antigen 96)-LPS interaction inhibitor
CAS 111797-22-9
MW: 358.4 D
From 48.00€ *
Review