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Leucettine L41
Item number: AG-MR-C0023-M005
Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3 alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against...
| Keywords: | (5Z)-5-(1,3-Benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4one |
| Application: | DYRK / CLK inhibitor |
| CAS | 1112978-84-3 |
| MW: | 307,3 D |
From 72.00€
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Leucettine L41
Item number: Cay29225-1
Leucettine L41 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 µM, respectively). It also inhibits GSK3alpha/beta and Pim1 with IC50 values of 0.41 and 4.1 µM, respectively. It inhibits...
| Keywords: | (5Z)-5-(1,3-benzodioxol-5-ylmethylene)-3,5-dihydro-2-(phenylamino)-4H-imidazol-4-one |
| Application: | DYRK1A / DYRK2 / CLK1 / CLK3 inhibitor |
| CAS | 1112978-84-3 |
| MW: | 307.3 D |
From 85.00€
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Leucettine L41
Item number: TGM-T24402-10mg
Description: Leucettine L41 is an effective dual cdc2-like kinase and DYRKs inhibitor. Target: Others. Smiles: C(\C=1C=C2C(=CC1)OCO2)=C/3\NC(NC4=CC=CC=C4)=NC3=O. References: Naert G, Ferré V, Meunier J, Keller E, Malmström S, Givalois L, Carreaux F, Bazureau JP, Maurice T. Leucettine L41, a DYRK1A-preferential...
| Keywords: | Leucettine-L41, LeucettineL41 |
| CAS | 1112978-84-3 |
| MW: | 307.309 D |
From 154.00€
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