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BYK204165
Item number: Cay21430-1
BYK204165 is a selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1, IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay). It is selective for PARP1 over PARP2 (IC50 = 4,168 nM for murine PARP2 in an enzyme assay). BYK204165 inhibits hydrogen peroxide-activated PARP in A549 human lung epithelial,...
| Keywords: | PARP Inhibitor XIV, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione |
| Application: | PARP1 inhibitor |
| CAS | 1104546-89-5 |
| MW: | 252.3 D |
From 56.00€
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BYK204165
Item number: TGM-T7896-100mg
Description: BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1, IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay). Target: PARP. Smiles: Cn1cccc1\C=C1\C(=O)NC(=O)c2ccccc12. References: Eltze T , Boer R , Wagner T , et al. Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as...
| Keywords: | RT-017290 |
| Application: | PARP1 inhibitor |
| CAS | 1104546-89-5 |
| MW: | 252.27 D |
From 38.00€
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