Cholestyramine is a bile acid sequestrant. It binds to bile acids in the intestine and inhibits their absorption, which increases the synthesis of bile acids from cholesterol in the liver, thereby lowering serum LDL levels. Cholestyramine reduces serum cholesterol levels and increases bile acid excretion in the...

Description: Cholestyramine (Cholestyramine resin), a bile acid-binding resin, inhibits intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol. Target: Others. Smiles: N.[Cl-].CCC(C)C.CCC(CC(C)c1ccccc1)c1ccc(C[N+](C)(C)C)cc1. References: Maugeais C, et al. rHDL...