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Meclizine (hydrochloride)
Meclizine (hydrochloride)

Item number: Cay14615-10

Meclizine is a histamine H1 receptor antagonist (Ki = 250 nM). Pretreatment with meclizine (2.5-30 mg/kg, i.p.) reduces ovalbumin-induced mast cell degranulation, edema, and leukocyte influx in rat lung. Formulations containing meclizine have been used in the treatment of motion sickness and vertigo.Formal Name:...
Keywords: NSC 28728, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine, dihydrochloride
Application: Histamine receptor H1 antagonist
CAS 1104-22-9
MW: 463.9 D
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