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TM5275
TM5275

Item number: Cay23151-1

TM5275 is an inhibitor of plasminogen activator inhibitor 1 (PAI-1, IC50 = 6.95 µM), a serine-protease inhibitor involved in thrombosis. TM5275 inhibits formation of a complex consisting of tissue plasminogen activator (tPA), PAI-1, and GFP on vascular endothelial cells (VECs) in vitro, prolonging the time that tPA...
Keywords: 5-chloro-2-[[2-[2-[4-(diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]-benzoic acid, monosodium salt
Application: PAI-1 inhibitor
CAS 1103926-82-4
MW: 544 D
From 53.00€ *
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TM5275 sodium
TM5275 sodium

Item number: TGM-T4255-100mg

Description: TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1). Target: PAI-1. Smiles: [Na+].[O-]C(=O)c1cc(Cl)ccc1NC(=O)COCC(=O)N1CCN(CC1)C(c1ccccc1)c1ccccc1. References: Izuhara Y, et al. A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic...
Keywords: TM5275 sodium salt
Application: PAI-1 inhibitor
CAS 1103926-82-4
MW: 543.98 D
From 34.00€ *
Review