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ITD 1
Item number: Cay23326-10
ITD 1 is an inhibitor of TGF-beta (IC50 = 0.85 µM). It is selective for TGF-beta in an SBE4/Smad reporter assay, providing 83% inhibition when used at a concentration of 2.5 µM, over activin A, which is inhibited by 51% when used at the same concentration. ITD 1 inhibits TGF-beta signaling by induction of TGF-beta...
| Keywords: | 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid, ethyl ester |
| Application: | TGF-beta inhibitor, TGF-beta receptor type II degradation inducer |
| CAS | 1099644-42-4 |
| MW: | 415.5 D |
From 139.00€
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ITD-1
Item number: TGM-T2273-100mg
Description: ITD-1 is a potent and highly selective TGFbeta pathway inhibitor. Target: TGF-beta/Smad. Smiles: CCOC(=O)C1=C(C)NC2=C(C1c1ccc(cc1)-c1ccccc1)C(=O)CC(C)(C)C2. References: Willems E, et al. Cell Stem Cell. 2012 Aug 3,11(2):242-252.
| Application: | TGF-beta inhibitor, TGF-beta receptor type II degradation inducer |
| CAS | 1099644-42-4 |
| MW: | 415.52 D |
From 32.00€
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