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Item number: Cay15552-10

CCT137690 is a potent inhibitor of Aurora kinases (IC50s = 15, 25 and 19 nM for Aurora A, B, and C, respectively). It also inhibits the receptor tyrosine kinase FLT3 as well as the constitutively active form of FLT3 bearing internal-tandem duplications (FLT3-ITD, IC50s = 1.2 and 4.9 nM, respectively). CCT137690 is...

Keywords:	6-bromo-7-[4-[(5-methyl-3-isoxazolyl)methyl]-1-piperazinyl]-2-[4-(4-methyl-1-piperazinyl)phenyl]-3H-imidazo[4,5-b]pyridine
Application:	Aurora kinase inhibitor
CAS	1095382-05-0
MW:	551.5 D

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