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Item number: TGM-T6393-100mg

Description: ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1. Target: Kinesin. Smiles: NCCCN([C@H](CC#C)c1nc2cc(Cl)ccc2c(=O)n1Nc1ccccc1)C(=O)c1cccc(Cl)c1F. References: Rosen L, et al. Annual Meeting of ASCO: abstract 3076

Application:	Eg5 inhibitor
CAS	1095253-39-6
MW:	552.43 D

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ARQ 621

Item number: Cay34329-1

ARQ 621 is an Eg5 inhibitor. It reduces tumor growth in a MIA PaCa-2 pancreatic cancer mouse xenograft model when administered at a dose of 6.25 mg/kgFormal Name: N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-benzamide. CAS Number:...

Keywords:	N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-be...
Application:	Eg5 inhibitor
CAS	1095253-39-6
MW:	552.4 D

From 49.00€ *

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