2 products were found matching "1093108-50-9"!

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Item number: TGM-T14565-100mg

Description: BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly...

Keywords:	Cmpd A, AP-761
Application:	Prostaglandin D2 receptor CRTH2/GPR44/CD294 antagonist
CAS	1093108-50-9
MW:	501.5 D

From 54.00€ *

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BI-671800

Item number: Cay27638-1

BI-671800 is an antagonist of the prostaglandin D2 (PGD2, Cay-12010) receptor CRTH2/DP2 (IC50 = 42 nM in a radioligand binding assay). It binds selectively to CRTH2/DP2 over DP1, thromboxane, and prostacyclin receptors (IC50s = 25.6, 62.6, and >100 µM, respectively). BI-671800 inhibits PGD2-induced shape change in...

Keywords:	AP-761, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]-5-pyrimidineacetic acid
Application:	Prostaglandin D2 receptor CRTH2/GPR44/CD294 antagonist
CAS	1093108-50-9
MW:	501.5 D

From 94.00€ *

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Review

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