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Item number: TGM-T11464-100mg

Description: GRL0617 is a selective and competitive noncovalent inhibitor of SARS-CoVPLpro and deubiquitinase (IC50: 0.6 µM, Ki: 0.49 µM). Target: SARS-CoV, DUB. Smiles: C[C@@H](NC(=O)c1cc(N)ccc1C)c1cccc2ccccc12. References: Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors...

CAS	1093070-16-6
MW:	304.39 D

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COVID-19 Research

GRL-0617

Item number: Cay33348-1

GRL-0617 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 papain-like proteases (PLpros, IC50s = 0.6 and 1.5 µM, respectively). It increases the viability of SARS-CoV-infected Vero E6 cells (EC50 = 14.5 µM). GRL-0617 (6.25-50 µM) reduces viral replication in...

Keywords:	5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-benzamide
Application:	SARS-CoV and SARS-CoV-2 PLpro inhibitor
CAS	1093070-16-6
MW:	304.4 D

From 45.00€ *

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